What complication is cocaine use during pregnancy most likely associated with?

Cocaine use during pregnancy is most likely associated with placental abruption. This serious condition occurs when the placenta detaches from the uterine wall before delivery, which can lead to significant complications for both the mother and the fetus. Cocaine's stimulant effects cause vasoconstriction, which can reduce blood flow to the placenta and contribute to the risk of premature separation.

In addition to placental abruption, cocaine use can lead to other adverse pregnancy outcomes, including fetal growth restriction and increased risk of preterm labor. Therefore, understanding the association between cocaine and placental abruption is crucial, as it highlights the importance of substance abuse prevention and intervention in pregnant individuals to protect maternal and fetal health.

Other complications listed, such as gestational diabetes, multiple births, and hyperemesis gravidarum, do not have a well-established link with cocaine use, making placental abruption the most pertinent concern in this context.