Which drug is known to cause a false positive for PCP on a urine drug screen?

Venlafaxine is known to potentially cause a false positive for phencyclidine (PCP) on urine drug screens. This occurrence is linked to the drug's metabolism and the similarities between the metabolites of venlafaxine and PCP. Drug screens often use immunoassays that can cross-react with various substances, and venlafaxine's chemical structure can lead to this false positive result.

When interpreting urine drug screens, it's important to consider the possibility of false positives and the medications that can influence these results. In clinical settings, confirmatory testing, like gas chromatography-mass spectrometry (GC-MS), would be necessary to accurately identify the presence of PCP, particularly when there's a suspicion of false positives due to other medications.