Which side effect is commonly associated with bupropion?

Bupropion is an atypical antidepressant that is primarily used to treat major depressive disorder and as an aid for smoking cessation. One notable side effect of bupropion is the increased risk of seizures, particularly at higher doses or in individuals with certain risk factors such as a history of seizures, eating disorders, or alcohol/substance withdrawal. This side effect is attributed to its mechanism of action, which involves the inhibition of dopamine and norepinephrine reuptake but does not affect serotonin levels.

The risk of seizures is a significant concern with bupropion, especially when the recommended maximum daily dose is exceeded. Understanding this side effect is crucial for medical professionals when prescribing bupropion, as it allows them to monitor for potential complications and guide patient management accordingly. The other side effects, while possible, do not carry the same level of risk associated with seizures, which is why identifying it as a commonly associated side effect is important in the context of using this medication.